課程資訊
課程名稱
藥物傳輸系統
Drug Delivery Systems 
開課學期
102-1 
授課對象
學程  奈米科技學程  
授課教師
黃義侑 
課號
Biomed7014 
課程識別碼
548 M0300 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期四2,3,4(9:10~12:10) 
上課地點
 
備註
本課程中文授課,使用英文教科書。教室:基醫505
總人數上限:30人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1021Biomed7014 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
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課程概述

一、課程簡介:
To provide the students with a broad spectrum of scientific information in a concise, systematic manner but with new vision and wider scope in drug delivery systems. Lectures include:
1. Concepts and System Design forthe Rate-Controlled Drug Delivery
2. Mathematical Modeling of Controlled Drug Delivery
3. Oral Drug Delivery and Delivery System
4. Mucosal Drug Delivery: Potential Routes for Noninvasive Systemic
Administration (Rectal & Oral musosa DDS)
5. Nasal/ Pulmonary Drug Delivery and Delivery System
6. Transdermal Drug Delivery and Delivery System
7. Ocular Drug Delivery and Delivery System
8. Polymers for Drug delivery, EVA, Silicone...
and Natural Biodegradable Polymer in Drug Delivery System
9. Synthetic Biodegradable Polymer in Drug Delivery System
10. Compartmental Models and Their Application
11. Drug Targeting
12. Liposome Drug Delivery
13. Study Report

二、先修課程:無

三、參考書目:
1. J.Siepmann, R.A. Siegel, M.J. Rathbone “Fundamentals and Applications of Controlled Release Drug Delivery” 2012 Springer
2. A.M. Hillery, A.W. Lloyd, J. Swarbrick “Drug delivery and Targeting for Pharmacists and Pharmaceutical Scientists” Taylor & Francis, 2001
3. L.V. Allen, N. G. Popovich, H. C. Ansel “Pharmaceutical Dosage Forms and Drug Delivery System” Lippincott Williams & Wilkins, 9th ed c2010
4. Drug delivery : principles and applications / Binghe Wang, Teruna Siahaan, Richard Soltero Wiley-Interscience, c2005
5. Enhancement in drug delivery / edited by Elka Touitou, Brian W. Barry Boca Raton : CRC Press, c2007
6. Design of controlled release drug delivery systems / [edited by] Xiaoling Li, Bhaskara R. Jasti New York : McGraw-Hill, c2006
7. Y.W. Chien “Novel Drug Delivery Systems” 1992 Marcel Dekker Inc.
8. 橋田 充 “生體內藥物送達學”
 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
待補 
參考書目
1.J.Siepmann, R.A. Siegel, M.J. Rathbone “Fundamentals and Applications of Controlled Release Drug Delivery” 2012 Spring
2.A.M. Hillery, A.W. Lloyd, J. Swarbrick “Drug delivery and Targeting for Pharmacists and Pharmaceutical Scientists” Taylor & Francis, 2001
3. Transport processes in in pharmaceutical systems 2000 W1 D842p     
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
平時 (20%) 期中考(25%) 
45% 
 
2. 
期末考 
30% 
 
3. 
期末報告及書面報告 
25% 
 
 
課程進度
週次
日期
單元主題
第1週
09/12  Drug Delivery: The Basic Concepts & Market Perspectives (核心能力四) 
第2週
09/19  中秋節 
第3週
09/26  Advanced Drug Delivery and Targeting: An Introduction (核心能力四) 
第4週
10/03  Rate Control in Drug Delivery and Targeting: Fundamentals and Applications to Implantable Systems (核心能力四) 
第5週
10/10  國慶日 
第6週
10/17  Drug Targeting Systems: Fundamentals and Applications to Parenteral Drug Delivery (核心能力四) 
第7週
10/24  第一次小考及DDS影片教學 
第8週
10/31  Oral Drug Delivery (核心能力四) 
第9週
11/07  Oral Trans-mucosal Drug Delivery (核心能力四) 
第10週
11/14  Transdermal Drug Delivery (核心能力四) 
第11週
11/21  Nasal Drug Delivery (核心能力四) 
第12週
11/28  Brain Drug Delivery (核心能力四) 
第13週
12/05  Student report (核心能力四) 
第14週
12/12  Student report (核心能力四) 
第15週
12/19  Liposome DDS 註:與生醫奈米合併上課 
第16週
12/26  Student report (核心能力四) 
第17週
01/02  Plasmid gene Delivery (核心能力四) 
第18週
01/09  期末考